An important clinical pearl: Risk for tendinopathy is far greater in older patients and those taking concomitant corticosteroids. The risk for tendon rupture (odds ratio, 3.1; 95% confidence interval, ... Add Yahoo as a preferred source to see more of our stories on Google.

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While the majority of people experience no lasting effects from fluoroquinolones, others find their lives permanently altered ... Thus, fluoroquinolone use is typically reserved for cases in which the benefits clearly outweigh the risks. The spectrum of activity, mechanisms of action and resistance, important resistance patterns, and adverse effects of commonly available fluoroquinolones (ie, ciprofloxacin, levofloxacin, moxifloxacin, delafloxacin) will be reviewed here. Resistance of Streptococcus pneumoniae to fluoroquinolones, doxycycline, and trimethoprim-sulfamethoxazole and its implications for treatment.

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