Medscape: When Is it Appropriate to Use Methotrexate for Ectopic Pregnancy in the Emergency Department? Methotrexate is a chemotherapeutic agent used as medical therapy for the treatment of ectopic pregnancy. Although it is most commonly administered intramuscularly, obstetricians may inject the ...

Context Explanation

When Is it Appropriate to Use Methotrexate for Ectopic Pregnancy in the Emergency Department? Overall success rates for intramuscular (IM) methotrexate were comparable between recurrent and primary ectopic pregnancy cases, but single-dose treatment was less effective in recurrent cases. The American Journal of Managed Care: Methotrexate, Leflunomide Treatment Associated With Increased Possibility of Adverse Pregnancy Outcomes in Patients With RA Pregnant female patients with rheumatoid arthritis (RA) treated with methotrexate and leflunomide within 3 months of conception faced an increased possibility of adverse pregnancy outcomes, ... Methotrexate, Leflunomide Treatment Associated With Increased Possibility of Adverse Pregnancy Outcomes in Patients With RA Please provide your email address to receive an email when new articles are posted on .

Insight Material

The overall failure rate of methotrexate was 25.3% for women with an ectopic pregnancy. Gravidity and elevated ...