ascopubs.org: Octreotide Alone or With Prednisone in Patients With Advanced Thymoma and Thymic Carcinoma: An Eastern Cooperative Oncology Group Phase II Trial Octreotide Alone or With Prednisone in Patients With Advanced Thymoma and Thymic Carcinoma: An Eastern Cooperative Oncology Group Phase II Trial Octreotide is a man-made protein that is similar to a hormone in the body called somatostatin. Octreotide lowers many substances in the body such as insulin and glucagon (involved in regulating blood sugar), growth hormone, and chemicals that affect digestion. Octreotide is used to treat acromegaly.

Context Explanation

Octreotide injection is used to treat severe diarrhea and other symptoms that occur with certain intestinal tumors (eg, vasoactive intestinal peptide tumors or VIPomas) or metastatic carcinoid tumors (tumors that has already spread in the body). Octreotide is an injection medication that treats high levels of the growth hormone caused by acromegaly. Acromegaly affects your body’s bones and tissues and causes them to grow in irregular ways. What is octreotide, and what is it used for?

Insight Material

Octreotide is a medication used in the treatment of acromegaly, a disorder associated with excessive blood levels of growth hormone, and severe, watery diarrhea caused by certain types of gastrointestinal (GI) tumors. Octreotide, sold under the brand name Sandostatin among others, is an octa peptide that mimics natural somatostatin pharmacologically, though it is a more potent inhibitor of growth hormone, glucagon, and insulin than the natural hormone. Octreotide is used to treat acromegaly (condition in which the body produces too much growth hormone, causing enlargement of the hands, feet, and facial features; joint pain; and other symptoms) in people who have been treated successfully with octreotide injection or lanreotide injection.